Oral Bioavailability of Insulin Contained in Polysaccharide Nanoparticles
نویسندگان
چکیده
منابع مشابه
Enhancement of oral bioavailability of insulin in humans.
OBJECTIVE The purpose of this study is to investigate oral absorption of 1, 2 and 3 U/kg oral insulin five test products with different particle sizes in comparison with 0.1 U/kg subcutaneous reference formulation. METHODS Twenty five healthy volunteers participated in five studies using a two-phase, two-sequence crossover design with washout period of one day. Mean disposition kinetics was d...
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ژورنال
عنوان ژورنال: Biomacromolecules
سال: 2007
ISSN: 1525-7797,1526-4602
DOI: 10.1021/bm0703923